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Introductory Human Physiology | Coursera

Introductory Human Physiology

About this course: In this course, students learn to recognize and to apply the basic concepts that govern integrated body function (as an intact organism) in the body's nine organ systems.

Created by: Duke University

Taught by: Jennifer Carbrey, Assistant Research Professor
Department of Cell Biology
Taught by: Emma Jakoi, Associate Research Professor
Department of Cell Biology

Commitment	22 hours of videos and assessments
Language	English, Subtitles: Chinese (Simplified)
How To Pass	Pass all graded assignments to complete the course.
User Ratings	4.7 stars Average User Rating 4.7See what learners said

Syllabus

WEEK 1

Welcome and Additional Resources

Start here!

1 video, 6 readings

Video: Course Introduction
Leyendo: Welcome to Human Physiology
Leyendo: How to Use Discussion Forums
Leyendo: Course Logistics
Leyendo: About Us
Leyendo: FAQ_Including Syllabus for Downloading
Leyendo: Get to Know Your Classmates

Homeostasis and Endocrine System

Welcome to Module 2 of Introductory Human Physiology! We begin our study of the human body with an overview of the basic concepts that underlie the functions of cells and organs within the body and their integration to maintain life. This is an important introduction to how physiologists view the body. We will return to these basic concepts again as we progress through the organs systems and consider how they respond to perturbations incurred in daily functions and in disease. The things to do this week are to watch the 6 videos, to answer the in-video questions, to read the notes for each topic, and to complete two problem sets (homeostasis, transporters & channels, and endocrine concepts). It will be most effective if you follow the sequence of videos. The notes provide a more detailed summary of each topic. We encourage you to find which resource (videos and/or notes) works best for you.We have included a set of problems to be completed as homework exercises. We strongly encourage you to complete these problems sets. They are not graded and are for your personal feedback. It has been our experience that these exercises are helpful in increasing understanding and retention of the newly learned materials.Please use the interactive forum as a means to exchange ideas, to ask questions, to form study groups and interest groups, and to meet your community. We will monitor the forum daily.Thank you for joining us. We are excited about sharing this educational experience with you. Welcome!

6 videos, 1 reading, 2 practice quizzes

Video: Homeostasis and Fluid Compartments
Video: Regulation of Homeostasis
Video: Transporters Pumps and Channels
Video: Solute and Water Transport
Cuestionario de práctica: Practice Problem Set: Transporters, Channels, and Homeostasis
Video: General Concepts
Video: Assessment and Pathology
Cuestionario de práctica: Practice Problem Set: Endocrine Concepts
Leyendo: Resources

Graded: Homeostasis and Endocrine System Exam

WEEK 2

The Nervous System

We hope you are enjoying the course! Last week's lectures can be challenging because we introduce many concepts that may be new to you. This module will allow you to apply some of the concepts that you learned last week and provide you with more concrete examples. In this module we will begin our tour of the various organ systems with the nervous system. We start by considering the function of the individual cells (neurons) and then how they interact as an integrative system. The nervous system provides rapid communication throughout the body coordinating the actions of trillions of cells. It responds to internal changes to the body as well as to changes in our external environment. This is a busy week. The things to do this week are to watch the 5 videos, to answer the in-video questions, to read the notes, and to complete the Nervous System problem set. We suggest that you read the notes, watch the videos, and answer the in-video questions before you start on the problem sets. The problem sets require you to apply your knowledge from the lectures so it is best to be fairly familiar with the material before tackling them. The problem sets are not graded, and there is no due-date for them.

5 videos, 2 readings, 1 practice quiz

Video: Introduction and Cell Types
Video: Membrane Potentials
Leyendo: How To Calaculate The Equilibrium Potential
Video: Action Potentials
Video: Methods of Communication
Video: Organization
Cuestionario de práctica: Practice Problem Set: The Nervous System
Leyendo: Resources

Graded: The Nervous System Exam

WEEK 3

The Senses and the Somatic Nervous System

In this module, we consider two types of cells: one that relays information to the central nervous system (brain) for interpretation and a second set, motor neurons which relay information away from the central nervous system to govern voluntary movement. The input pathway to the brain is mediated by specific cells called senses. The senses convert energy (such as light or heat) into an energy form (electrical potentials) recognized by neurons in the brain. The brain, in turn, interprets this information (as vision or pain) and then sends out a motor response via the motor neurons of the somatic nervous system to effector cells in the body. The motor neurons activate skeletal muscle to control breathing and the movement of the limbs. The things to do this week are to watch the 5 videos, to answer the in-video questions, to read the notes, and to complete the problem set. It will be most effective if you follow the sequence of videos. The notes provide a more detailed summary of each topic. We encourage you to find which resource (videos and/or notes) works best for you and to try the problems sets. The problem sets are not graded. Both your understanding and retention will increase with application of the new learned information.

5 videos, 1 reading, 1 practice quiz

Video: Introduction and Vision
Video: Hearing and the Vestibular System
Video: Chemical Senses
Video: Intro and Structure
Video: Control of Movement
Cuestionario de práctica: Practice Problem Set: Senses and Nervous System
Leyendo: Resources

Graded: The Senses and the Somatic Nervous System Exam

WEEK 4

Muscle

In this module, we consider the effectors of the body that govern voluntary and involuntary movement. These effectors are specialized cells called muscle which are capable of generating force (tension). Muscle cells are classified as one of three types: skeletal, smooth, and cardiac. Although all three types generate tension, each is specialized for a given function. Skeletal muscle governs voluntary movement of the limbs and is critical for expansion of the lung during breathing. Smooth and cardiac muscle are contractile cells found in the walls of blood vessels and the heart, respectively. We will return to the basic principles that govern these cells types when we consider the respiratory and cardiovascular systems. The things to do this week are to watch the 4 videos, to answer the in-video questions, to read the notes, and to complete two problem sets (skeletal muscle and smooth & cardiac muscle). It will be most effective if you follow the sequence of videos. The notes provide a more detailed summary of each topic. We encourage you to find which resource (videos and/or notes) works best for you and to try the problems sets. The problem sets are not graded. Both your understanding and retention will increase with application of the new learned information.

4 videos, 1 reading, 2 practice quizzes

Video: Intro and Contraction
Video: Tension and Metabolism
Cuestionario de práctica: Practice Problem Set: Skeletal Muscle
Video: Smooth Muscle Structure, Regulation and Pacemakers
Video: Cardiac Muscle Structure, E-C Coupling and Force Generation
Cuestionario de práctica: Practice Problem Set: Smooth and Cardiac Muscle
Leyendo: Resources

Graded: Muscle Exam

WEEK 5

Cardiovascular System

Welcome back! In this module we consider how the circulatory system works to deliver oxygen and nutrients to the specific organs. We start with a discussion of the electrical and mechanical functions of the heart which enable it to generate a pressure gradient. This pressure gradient propels the blood through the blood vessels, in a unidirectional manner. The following session considers the factors that govern delivery of gases and nutrients at the tissue level. The last session considers the entire reflex loop, its control, and its response to daily demands (rest and exercise) and how pathology affects these responses. This is a busy week! The things to do this week are to watch the 5 videos, to answer the in-video questions, to read the notes, and to complete the CV problem set. It will be most effective if you follow the sequence of videos. The notes provide a more detailed summary of each topic. We encourage you to find which resource (videos and/or notes) works best for you and to try the problems sets. The problem sets are not graded. Both your understanding and retention will increase with application of the new learned information.

5 videos, 1 reading, 1 practice quiz

Video: Heart Electrical Activity
Video: Heart As A Pump
Video: Cardiac Performance
Video: Circulatory System
Video: Reflex Control
Cuestionario de práctica: Practice Problem Set: The Cardiovascular System
Leyendo: Resources

Graded: Cardiovascular System Exam

WEEK 6

Respiratory System

We hope that you are enjoying the course! This module considers the respiratory system. In these lessons, we explore topics such as how we get air into our lungs, the role of airway resistance in ventilation, the transport of oxygen and carbon dioxide between the lungs and tissues, and the regulation of breathing. There are a couple of demonstrations of lung function in the videos! The things to do this week are to watch the 8 videos, to answer the in-video questions, to read the notes, and to complete the Respiratory System problem set. We suggest that you read the notes, watch the videos, and answer the in-video questions before you start on the problem sets, which are not graded. Take a deep breath and have fun with it!

8 videos, 1 reading, 1 practice quiz

Video: Anatomy and Mechanics
Video: Lung Volumes and Compliance
Video: Pressure Changes and Resistance
Video: Pulmonary Function Tests and Alveolar Ventilation
Video: Oxygen Transport
Video: CO2 Transport and V/Q Mismatch
Video: Exercise and Hypoxia
Video: Regulation of Breathing
Cuestionario de práctica: Practice Problem Set: The Respiratory System
Leyendo: Resources

Graded: Respiratory System Exam

WEEK 7

The Endocrine System

IIn this module, we return our attention to the endocrine system and its role in the maintenance of homeostasis. In particular we consider the hypothalamus-pituitary axis, which integrates signals from the nervous system and from the blood to regulate most homeostatic functions, including growth, ion balance, fluid balance, response to stress, and energy use. The first lesson gives an overview of the hypothalamus-pituitary axis and its actions in regulating growth of the body. In later lessons we consider how this complex negative feedback loop governs the body’s energy use and its response to stress. Then, later in lesson 3, we turn our attention to the simple reflex loop by which the endocrine pancreas regulates metabolism in both the fed and fasted states and the failures of this system (diabetes mellitus). The hypothalamus-pituitary axis and its control of reproduction in both males and females are considered in the next module (Module 9). The things to do this week are to watch the 6 videos, to answer the in-video questions, to read the notes, and to do the two problem sets (endocrine system and fuel homeostasis). Please note that each module can stand alone, however, it will be most effective if you do the first two videos (H-P-axis) before any of the others. The notes provide a more detailed summary of each topic and again we encourage you to use the resource (videos and/or notes) that works best for you. Please do try the problems sets for self-review. Both your understanding and retention will increase with application of the new learned information.

6 videos, 1 reading, 2 practice quizzes

Video: Hypothalamus-Anterior Pituitary Axis- GH
Video: Hypothalamus-Posterior Pituitary Axis
Video: Hypothalamus-Pituitary- Adrenal Axis
Video: Hypothalamus-Pituitary-Thyroid Axis
Cuestionario de práctica: Practice Problem Set: The Endocrine System
Video: Fed State & Insulin
Video: Fasted State and Glucagon
Cuestionario de práctica: Practice Problem Set: Fuel Homeostasis
Leyendo: Resources

Graded: The Endocrine System Exam

WEEK 8

The Reproductive System

Welcome back! This module continues our discussion of the endocrine system and its control of homeostasis. In this series of videos, we consider how the endocrine system regulates the production of gametes (egg and sperm) in the female and male, respectively, as well as the production of the sex hormones. The things to do this week are to watch the 4 videos, to answer the in-video questions, to read the notes, and to complete the problem set. It will be most effective if you follow the sequence of the lectures on the reproductive system. Again please consult the notes for a more detailed summary of each topic. If you have not tried the problems sets, please do so. They will reinforce your understanding of the newly learned information by applying it. Since these problem sets are delivered in the same electronic format as the exams, by completing them, you will gain confidence in using the electronic test format.

4 videos, 1 reading, 1 practice quiz

Video: Hypothalamus-Pituitary-Gonad Axis
Video: Sperm and Hormone Production
Video: Hypothalamus-Pituitary-Gonad Axis
Video: Menstrual Cycle
Cuestionario de práctica: Practice Problem Set: The Reproductive System
Leyendo: Resources

Graded: The Reproductive System Exam

WEEK 9

The Gastrointestinal System

Congratulations! You have almost completed this course. In this module, we consider the inner workings of your gut. Most of our discussions deal with the function of specific regions of the gastrointestinal tract where complex foods are processed into solutes and nutrients that can be absorbed into the body for use as fuel. This “processing plant” acts in a unidirectional manner from mouth to anus and requires the coordinated secretions of acid, enzymes, bases, and fluids for its normal function. What is unusual about the gastrointestinal (GI) tract and its accessory organs, salivary glands, liver, and pancreas, is that their coordinated actions occur in a timely manner without conscious input from the brain. Instead the gut integrates its diverse actions by locally produced chemicals (hormones and paracrines) as well as by the coordinated actions of the enteric nervous system, a subdivision of the autonomic nervous system. In the last lesson of this module, we consider normal motility of the gut, as well as perturbations that result in gastrointestinal distress such as vomiting and diarrhea. The things to do this week are to watch the 4 videos, to answer the in-video questions, to read the notes, and to complete the gastrointestinal problem set. For this topic, the most effective approach will be to follow the sequence of videos as we move along the gastrointestinal tract. The notes provide a more detailed summary of the video lectures. Again, please use the resource (videos and/or notes) that works best for you. However, we encourage you to complete the problem sets as both your understanding and retention will increase with application of the new learned information. Hope you enjoy the week!

4 videos, 1 reading, 1 practice quiz

Video: General Structure and Function
Video: Regulation of Acid Secretion
Video: Digestion and Absorptio
Video: Motility
Cuestionario de práctica: Practice Problem Set: The Gastrointestinal System
Leyendo: Resources

Graded: The Gastrointestinal System Exam

WEEK 10

The Urinary System

Welcome to module 11 and the last organ system to be covered in this course! In this module, we turn our attention to the urinary system and specifically to the functions of the kidney, a filter of the blood. The kidney is a complicated organ whose actions integrate with those of the cardiovascular system to maintain blood pressure and with the respiratory system to maintain acid-base balance. As we progress through this module, we consider the mechanisms by which the kidney regulates the water content and the electrolyte content of the body. We focus on the roles of the normal kidney but also consider changes in homeostasis due to either disease or drugs. The last lesson of this module considers the role of the kidney in regulating acid-base balance of the body and its integration with the respiratory system. The things to do this week are to watch the 6 videos, to answer the in-video questions, to read the notes, and to complete one problem set (urinary system). In this module, the sequence of videos is important. As you proceed through the videos and notes, try to correlate the specific region of the renal tubule with its function. Often this is best achieved by drawing the renal tubule and labeling the specific changes in structure and function. Again, the notes will provide a more detailed summary of the material presented in the videos. Please note that the first two videos correlate with the first set of notes and the third video with the second set of notes. We encourage you to complete the problem set. The problem set is not graded and is for your personal feedback. Both your understanding and retention will increase with application of the new learned information.

6 videos, 1 reading, 1 practice quiz

Video: General Structure and Function
Video: Filtration Rate and Regulation
Video: Reabsorption and Secretion
Video: Regulation of Fluid Balance
Video: General Concepts and Renal Tubule Function
Video: Balance, Disturbances, and Analysis
Cuestionario de práctica: Practice Problem Set: The Urinary System
Leyendo: Resources

Graded: The Urinary System Exam

FAQs

When will I have access to the lectures and assignments?

What if I need additional time to complete the course?

Can I take this course for free?

What is the refund policy?

Is financial aid available?

How It Works

Trabajo del curso

Cada curso es como un libro de texto interactivo, con videos pregrabados, cuestionarios y proyectos.

Ayuda de tus compañeros

Conéctate con miles de estudiantes y debate ideas y materiales del curso, y obtén ayuda para dominar los conceptos.

Certificados

Obtén reconocimiento oficial por tu trabajo y comparte tu éxito con amigos, compañeros y empleadores.

Creators

Duke University

Duke University has about 13,000 undergraduate and graduate students and a world-class faculty helping to expand the frontiers of knowledge. The university has a strong commitment to applying knowledge in service to society, both near its North Carolina campus and around the world.

Ratings and Reviews

Rated 4.7 out of 5 of 1,358 ratings

very useful course

greatky

it is an amazing course it really helps me but i hope that it was been with Arabic subtitles on the vedios

Awesome :)

TBILISI GEORGIA

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Asia

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Austria

B

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C

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Latvia

Liechtenstein

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Macedonia F.Y.R.

Malta

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N

Netherlands

Norway

P

Poland

Portugal

R

Romania

Russia

S

San Marino

Serbia

Slovakia

Slovenia

Spain

Svalbard And Jan Mayen

Sweden

Switzerland

T

Turkey

U

Ukraine

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V

Vatican
A

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B

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Barbados

Belize

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Bolivia

Bonaire, Saint Eustatius and Saba

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C

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Jamaica

M

Martinique

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N

Nicaragua

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Panama

Paraguay

Peru

Puerto Rico

S

Saint Barthelemy

Saint Kitts and Nevis

Saint Lucia

Saint Martin

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South Georgia and The South Sandwich Islands

Suriname

T

Trinidad and Tobago

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U.S. Virgin Islands

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B

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Gambia

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Libya

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Malawi

Mali

Mauritania

Morocco

Mozambique

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Niger

Nigeria

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Rwanda

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Saint Helena

Sao Tome and Principe

Senegal

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Somalia

South Africa

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Sudan

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Tunisia

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Uganda

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Western Sahara

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Zambia

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A

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B

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Bhutan

British Indian Ocean Territory

Brunei

C

Cambodia

China

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Comoros

E

East Timor

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French Southern Territories

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Georgia

H

Hong Kong

I

India

Indonesia

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Israel

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Japan

Jordan

K

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Kuwait

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Laos

Lebanon

M

Macao

Madagascar

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N

Nepal

North Korea

O

Oman

P

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R

Reunion

S

Saudi Arabia

Seychelles

Singapore

South Korea

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T

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Thailand

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U

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Y

Yemen
A

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Kiribati

M

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Northern Mariana Islands

P

Palau

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Samoa

Solomon Islands

T

Tokelau

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Vanuatu

W

Wallis and Futuna

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Regions:

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Name	Weather forecast	Altitiude	Population
Tbilisi	Today \| Tomorrow \| 7 days	420m	1049498
Art’ana	Today \| Tomorrow \| 7 days	484m	n/a
Bagebi	Today \| Tomorrow \| 7 days	859m	n/a
Jugaani	Today \| Tomorrow \| 7 days	450m	n/a
Lalisquri	Today \| Tomorrow \| 7 days	441m	n/a
Lap’anquri	Today \| Tomorrow \| 7 days	598m	n/a
Lech’uri	Today \| Tomorrow \| 7 days	577m	n/a
Saniore	Today \| Tomorrow \| 7 days	448m	n/a

Name	Weather forecast	Forecast for altitude			Hotels
Gora Shkhara	Today \| Tomorrow \| 7 days	5068m	3028m	2169m	2 Hotels
Gora Dzhangitau	Today \| Tomorrow \| 7 days	5058m	3523m	2121m	2 Hotels
Mt'a Mqinvartsveri	Today \| Tomorrow \| 7 days	5033m	3577m	2253m	8 Hotels
Gora Tetnul'd	Today \| Tomorrow \| 7 days	4852m	3523m	2121m	7 Hotels
M’ta Ushba	Today \| Tomorrow \| 7 days	4700m	2898m	1700m	19 Hotels
Gora Tebulosmta	Today \| Tomorrow \| 7 days	4493m	2654m	1738m	2 Hotels
Mt'a Shani	Today \| Tomorrow \| 7 days	4451m	3286m	1869m	7 Hotels
Gora Diklosmta	Today \| Tomorrow \| 7 days	4285m	2492m	1920m	2 Hotels
Gora Komito	Today \| Tomorrow \| 7 days	4261m	2934m	1943m	2 Hotels
Gora Kuru	Today \| Tomorrow \| 7 days	4071m	2349m	1766m	8 Hotels
Gora Shino	Today \| Tomorrow \| 7 days	4047m	2651m	1766m	7 Hotels
Gora Dombay-Ul’gen	Today \| Tomorrow \| 7 days	4016m	2997m	864m	5 Hotels
Mt’a Lahili	Today \| Tomorrow \| 7 days	4010m	3063m	1676m	19 Hotels
Mt’a Shdavleri	Today \| Tomorrow \| 7 days	3996m	3089m	1215m	19 Hotels
Mt'a Ts'alsagi	Today \| Tomorrow \| 7 days	3992m	3015m	1494m	19 Hotels
Gora Layla	Today \| Tomorrow \| 7 days	3985m	3063m	1676m	19 Hotels
Gora Gvandra	Today \| Tomorrow \| 7 days	3983m	2780m	1251m	17 Hotels
Mt'a Khalatsa	Today \| Tomorrow \| 7 days	3938m	3030m	1679m	1 Hotels
Gora Ertsog	Today \| Tomorrow \| 7 days	3910m	3026m	1352m	5 Hotels
Gora Zilgakhokh	Today \| Tomorrow \| 7 days	3856m	2137m	1638m	7 Hotels
Gora Moguashirkha	Today \| Tomorrow \| 7 days	3852m	2780m	1251m	12 Hotels
Gora Chaikhi-Severnaya	Today \| Tomorrow \| 7 days	3842m	2958m	1625m	7 Hotels
Mt’a Amugo	Today \| Tomorrow \| 7 days	3840m	2364m	1700m	2 Hotels
Gora Tsitiaup	Today \| Tomorrow \| 7 days	3832m	2882m	1638m	7 Hotels
Gora Pshish	Today \| Tomorrow \| 7 days	3790m	2839m	1559m	5 Hotels
P'asismt'a	Today \| Tomorrow \| 7 days	3779m	2895m	1598m	1 Hotels
Gora Ullu-Tau-Chana	Today \| Tomorrow \| 7 days	3776m	2462m	1694m	19 Hotels
Gora Sakashil-Bash	Today \| Tomorrow \| 7 days	3776m	2462m	1694m	19 Hotels
Gora Leyrak	Today \| Tomorrow \| 7 days	3754m	2283m	1494m	19 Hotels
Mt’a Khorisari	Today \| Tomorrow \| 7 days	3738m	2471m	1689m	7 Hotels
Gora Gimarakhokh	Today \| Tomorrow \| 7 days	3716m	2378m	1489m	7 Hotels
Gora Kharikhra	Today \| Tomorrow \| 7 days	3710m	2608m	1476m	11 Hotels
Gora Sherkhota	Today \| Tomorrow \| 7 days	3694m	2379m	1606m	7 Hotels
Gora Lazg-Tsiti	Today \| Tomorrow \| 7 days	3693m	2882m	1638m	7 Hotels
Gora Chaukhi	Today \| Tomorrow \| 7 days	3688m	2347m	1625m	7 Hotels
Gora Sherkhota	Today \| Tomorrow \| 7 days	3670m	2503m	1640m	7 Hotels
Gora Bursamdzeli	Today \| Tomorrow \| 7 days	3661m	2449m	1534m	4 Hotels
Gora Maamgov	Today \| Tomorrow \| 7 days	3608m	2560m	1640m	5 Hotels
Mt’a Moda	Today \| Tomorrow \| 7 days	3608m	2208m	1315m	1 Hotels
Gora Esikom	Today \| Tomorrow \| 7 days	3587m	2161m	1561m	7 Hotels

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Name Weather forecast Base altitude Top altitude Hotels

Bakuriani Today | Tomorrow | 7 days | Weekend 1700m 2200m 16 Hotels

Gudauri Today | Tomorrow | 7 days | Weekend 2158m 3358m 7 Hotels

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Name	Weather forecast	Altitiude	Attractions	Hotels
Batumi	Today \| Tomorrow \| 7 days \| Weekend	0m	4	62 Hotels
Kobuleti	Today \| Tomorrow \| 7 days \| Weekend	0m	4	62 Hotels
Kutaisi	Today \| Tomorrow \| 7 days \| Weekend	0m	3	11 Hotels
Mazeri	Today \| Tomorrow \| 7 days \| Weekend	1700m	1	19 Hotels
Mestia	Today \| Tomorrow \| 7 days \| Weekend	1417m	0	19 Hotels
Poti	Today \| Tomorrow \| 7 days \| Weekend	0m	1	17 Hotels
Sukhumi	Today \| Tomorrow \| 7 days \| Weekend	0m	2	5 Hotels